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These effects indicated that improved expression of your Ex4a(+)WT1 isoform could lead to your induction of apoptosis. What's more, to look at the results in the endogenous Ex4a(+)WT1 isoform on Dox-induced apoptosis, K562 cells were transfected with both of two different WT1 Ex4a-specific siRNAs (si-4a-1 and si-4a-2) or manage siRNA (si-control) for twenty-four h, handled with Dox for twelve h, a